Applications of Croscarmellose Sodium
- Used in formulations as a disintegrant for capsules, tablets, and granules.
- In wet granulations, DISOTAB can be added in both the wet and dry stages of the process so that the wicking and swelling ability of the disintegrant is best utilized.
- Concentrations of normally 2% w/w is used in tablets in direct compression and 3% w/w in tablets in wet-granulation process.
- Suitable for products where the use of starch products is contraindicated.
- Works by attracting water into the tablet pores (wicking) followed by swelling.
